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Progesterone metabolomics and neurosteroids
The least understood and most relevant hormone in perimenopause. Biosynthesis, 5-alpha reductase, allopregnanolone and cognitive function.
Subtopics
- 7.1Progesterone biosynthesis: the full pathway
- 7.25-alpha reductase and conversion to allopregnanolone
- 7.3Allopregnanolone as a neurosteroid
- 7.4Progesterone deficit in perimenopause
- 7.5Urinary progesterone metabolites as biomarkers
- 7.6Progesterone and cognitive function: neuroprotection vs neurodestruction